Anjos Macedo

senior researcher

Assistant Professor (since 1994)
Phone number
(+351) 212948356 (ext: 10939)
Ciência Vitae

Recent publications

  • Viegas, CSB; Araujo, N; Carreira, J; Pontes, JF; Macedo, AL; Vinhas, M; Moreira, AS; Faria, TQ; Grenha, A; de Matos, AA; Schurgers, L; Vermeer, C; Simes, DC. 2022. Nanoencapsulation of Gla-Rich Protein (GRP) as a Novel Approach to Target Inflammation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23, DOI: 10.3390/ijms23094813
  • Goodfellow, BJ; Freire, F; Carvalho, AL; Aveiro, SS; Charbonnier, P; Moulis, JM; Delgado, L; Ferreira, GC; Rodrigues, JE; Poussin-Courmontagne, P; Birck, C; McEwen, A; Macedo, AL. 2021. The SOUL family of heme-binding proteins: Structure and function 15 years later. COORDINATION CHEMISTRY REVIEWS, 448, DOI: 10.1016/j.ccr.2021.214189
  • Araujo, N; Viegas, C; Pontes, JF; Marreiros, C; Raimundo, P; Macedo, AL; de Matos, AA; Grenha, A; Vermeer, C; Simes, DC. 2021. YY Nanoencapsulation as a novel delivery approach for therapeutic applications of gla-rich protein (GRP). ANNALS OF MEDICINE, 53, DOI: 10.1080/07853890.2021.1896900
  • Caldeira, J; Almeida, G; Macedo, AL; Silva, JPM; Albergaria, H. 2019. Saccharomycin, a biocide from S. cerevisiae that kill-off other yeasts. ANNALS OF MEDICINE, 51, DOI: 10.1080/07853890.2018.1562694
  • Cerofolini, L; Silva, JM; Ravera, E; Romanelli, M; Geraldes, CFGC; Macedo, AL; Fragai, M; Parigi, G; Luchinat, C. 2019. How Do Nuclei Couple to the Magnetic Moment of a Paramagnetic Center? A New Theory at the Gauntlet of the Experiments. Journal of Physical Chemistry Letters, 10, DOI: 10.1021/acs.jpclett.9b01128
  • Silva, JM; Giuntini, S; Cerofolini, L; Geraldes, CFGC; Macedo, AL; Ravera, E; Fragai, M; Luchinat, C; Calderone, V. 2019. Non-crystallographic symmetry in proteins: Jahn-Teller-like and Butterfly-like effects?. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 24, DOI: 10.1007/s00775-018-1630-0
  • Silva, JM; Cerofolini, L; Giuntini, S; Calderone, V; Geraldes, CFGC; Macedo, AL; Parigi, G; Fragai, M; Ravera, E; Luchinat, C. 2019. Metal centers in biomolecular solid-state NMR. JOURNAL OF STRUCTURAL BIOLOGY, 206, DOI: 10.1016/j.jsb.2018.11.013
  • Viegas, CSB; Santos, L; Macedo, AL; Matos, AA; Silva, AP; Neves, PL; Staes, A; Gevaert, K; Morais, R; Vermeer, C; Schurgers, L; Simes, DC. 2018. Chronic Kidney Disease Circulating Calciprotein Particles and Extracellular Vesicles Promote Vascular Calcification: A Role for GRP (Gla-Rich Protein). ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 38, DOI: 10.1161/ATVBAHA.117.310578
  • Viegas, CSB; Costa, RM; Santos, L; Videira, PA; Silva, Z; Araujo, N; Macedo, AL; Matos, AP; Vermeer, C; Simes, DC. 2017. Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases. PLoS One, 12, DOI: 10.1371/journal.pone.0177829
  • Zamora-Carreras, H; Torres, M; Bustamante, N; Macedo, AL; Rodriguez, R; Villalba, M; Bruix, M. 2015. The C-terminal domains of two homologous Oleaceae beta-1,3-glucanases recognise carbohydrates differently: Laminarin binding by NMR. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 580, DOI: 10.1016/

Main research interests

  • Understanding biomolecular function in disease
  • - Gla-rich proteins in vascular calcification events (Col. D. Simes, CCMAR - UAlg & AP Matos, CiiEM)
  • - NMR applications in Paramagnetic Systems / Metalloproteins (col. C. Luchinat, CERM, UFlorence & C.Geraldes, UCoimbra - joint PhD project | José Pedro Silva (grant #PD/BD/135180/2017))
  • - NMR Structural studies of proteins and peptides:
  • -- Antimicrobial Peptides; mode of action (col. H.Albergaria, LNEG)
  • -- Heme binding proteins and heme scavenging solutions (collaboration: B. Goodfellow, UAveiro and M. Picciolli, CERM, UFlorence)