Cristiano Mota

senior researcher

CEEC Individual Assistant Researcher (since 2023)
Phone number
+351212948300 (ext: 10962)
Ciência Vitae

Recent publications

  • Vilela-Alves, G; Manuel, RR; Oliveira, AR; Pereira, IC; Romao, MJ; Mota, C. 2023. Tracking W-Formate Dehydrogenase Structural Changes During Catalysis and Enzyme Reoxidation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24, DOI: 10.3390/ijms24010476
  • Oliveira, AR; Mota, C; Klymanska, K; Biaso, F; Romao, MJ; Guigliarelli, B; Pereira, IC. 2022. Spectroscopic and Structural Characterization of Reduced Desulfovibrio vulgaris Hildenborough W-FdhAB Reveals Stable Metal Coordination during Catalysis. ACS Chemical Biology, 17, DOI: 10.1021/acschembio.2c00336
  • Mota, C; Diniz, A; Coelho, C; Santos-Silva, T; Esmaeeli, M; Leimkuhler, S; Cabrita, EJ; Marcelo, F; Romao, MJ. 2021. Interrogating the Inhibition Mechanisms of Human Aldehyde Oxidase by X-ray Crystallography and NMR Spectroscopy: The Raloxifene Case. JOURNAL OF MEDICINAL CHEMISTRY, 64, DOI: 10.1021/acs.jmedchem.1c01125
  • Oliveira, AR; Mota, C; Mourato, C; Domingos, RM; Santos, MFA; Gesto, D; Guigliarelli, B; Santos-Silva, T; Romao, MJ; Pereira, IAC. 2020. Toward the Mechanistic Understanding of Enzymatic CO2 Reduction. ACS Catalysis, 10, DOI: 10.1021/acscatal.0c00086

Main research interests

  • Metalloenzymes and their catalytic mechanisms. Focus on Mo- and W- enzymes (Formate dehydrogenase, Aldehyde oxidases, ...)
  • Structural Biology
  • X-ray crystallography and time-resolved approaches