People
João Pedro Silva
senior researcher
Email
jpmsilva@ff.up.pt
Lab
Phone number
+351 220428000 (ext: 8796)
ORCID
Ciência Vitae
Recent publications
- Ana Margarida Araújo; Sandra IMarques; Paula Guedes de Pinho; Helena Carmo; Félix Carvalho; João Pedro Silva. 2024. Identification of key neuronal mechanisms triggered by dimethyl fumarate in SH-SY5Y human neuroblastoma cells through a metabolomic approach. ARCHIVES OF TOXICOLOGY, DOI: 10.1007/s00204-024-03683-9
- Marques, SI; Carmo, H; Carvalho, F; Sa, SI; Silva, JP. 2023. A Semi-Automatic Method for the Quantification of Astrocyte Number and Branching in Bulk Immunohistochemistry Images. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24, DOI: 10.3390/ijms24054508
- R Roque-Bravo, R Silva, H Carmo, F Carvalho, D Dias-da-Silva, João P Silva. 2023. Synthetic Cannabinoids: A Pharmacological and Toxicological Overview. Annual Review of Pharmacology and Toxicology, 63, DOI: 10.1146/annurev-pharmtox-031122-113758
- TM Gomes, D Dias da Silva, H Carmo, F Carvalho, JP Silva. 2020. Epigenetics and the endocannabinoid system signaling: an intricate interplay modulating neurodevelopment. PHARMACOLOGICAL RESEARCH, DOI: 10.1016/j.phrs.2020.105237
- J Alexandre, R Malheiro, DD Silva, H Carmo, F Carvalho, JP Silva. 2020. The Synthetic Cannabinoids THJ-2201 and 5F-PB22 Enhance In Vitro CB1 Receptor-Mediated Neuronal Differentiation at Biologically Relevant Concentrations. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(17), DOI: 10.3390/ijms21176277
- Silva JP, Andronis C, Lekka E, Virvilis V, Carmo H, Bampali K, Ernst M, Hu Y, Loryan I, Richard J, Carvalho F, Savić MM.. 2020. Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis. ARCHIVES OF TOXICOLOGY, DOI: 10.1007/s00204-020-02788-1
Main research interests
- Molecular Toxicology
- Toxicological signatures of Synthetic cannabinoids
- New Psychoactive Substances effects on neuronal development
- Substances of abuse-induced epigenetic changes
- In vitro models of neurotoxicity