People

Helena Coelho

Junior Researcher

Position
CEEC Individual Junior Researcher (since 2021)
Email
h.coelho@fct.unl.pt
Phone number
212948300 (ext: 10908)
Ciência Vitae

Recent publications

  • Maria Pia Lenza; Leire Egia-Mendikute; Asier Antoñana-Vildosola; Cátia OSoares; Helena Coelho; Francisco Corzana; Alexandre Bosch; Prodhi Manisha; Jon Imanol Quintana; Iker Oyenarte; Luca Unione; María Jesús Moure; Mikel Azkargorta; Unai Atxabal; Klaudia Sobczak; Felix Elortza; James DSutherland; Rosa Barrio; Filipa Marcelo; Jesús Jiménez-Barbero; Asis Palazon; June Ereño-Orbea. 2023. Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b. Nature Communications, DOI: 10.1038/s41467-023-39119-8
  • Andres Manuel Gonzalez-Ramirez and Ana Sofia Grosso and Zhang Yang and Ismael Companon and Helena Coelho and Yoshiki Narimatsu and Henrik Clausen and Filipa Marcelo and Francisco Corzana and Ramon Hurtado-Guerrero. 2022. Structural basis for the synthesis of the core 1 structure by C1GalT1. Nature Communications, 13, DOI: 10.1038/s41467-022-29833-0
  • Coelho, Helena; Rivas, Matilde De Las; Grosso, Ana S.; Diniz, Ana; Soares, Cátia O.; Francisco, Rodrigo A.; Dias, Jorge S.; Compañon, Ismael; Sun, Lingbo; Narimatsu, Yoshiki; Vakhrushev, Sergey Y.; Clausen, Henrik; Cabrita, Eurico J.; Jiménez-barbero, Jesús; Corzana, Francisco; Hurtado-guerrero, Ramon; Marcelo, Filipa. 2022. Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling. JACS Au, DOI: 10.1021/jacsau.1c00529
  • Lima, CDL; Coelho, H; Gimeno, A; Trovao, F; Diniz, A; Dias, JS; Jimenez-Barbero, J; Corzana, F; Carvalho, AL; Cabrita, EJ; Marcelo, F. 2021. Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune-Related Lectins. CHEMISTRY-A EUROPEAN JOURNAL, DOI: 10.1002/chem.202100800
  • Lenza, MP; Oyenarte, I; Diercks, T; Quintana, JI; Gimeno, A; Coelho, H; Diniz, A; Peccati, F; Delgado, S; Bosch, A; Valle, M; Millet, O; Abrescia, NGA; Palazon, A; Marcelo, F; Jimenez-Oses, G; Jimenez-Barbero, J; Arda, A; Ereno-Orbea, J. 2020. Structural Characterization of N-Linked Glycans in the Receptor Binding Domain of the SARS-CoV-2 Spike Protein and their Interactions with Human Lectins. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, DOI: 10.1002/anie.202011015
  • Matilde de las Rivas, Helena Coelho, Ana Diniz, Erandi Lira-Navarrete, Ismael Compañón, Jesús Jiménez-Barbero, Katrine T. Schjoldager, Eric P. Bennett, Sergey Y. Vakhrushev, Henrik Clausen, Francisco Corzana, Filipa Marcelo, Ramon Hurtado-Guerrero. 2018. Structural analysis of a GalNAc‐T2 mutant reveals an induced‐fit catalytic mechanism for GalNAc‐Ts. Chemistry – A European Journal, 24, DOI: 10.1002/chem.201800701
  • Coelho, H; Matsushita, T; Artigas, G; Hinou, H; Canada, FJ; Lo-Man, R; Leclerc, C; Cabrita, EJ; Jimenez-Barbero, J; Nishimura, S; Garcia-Martin, F; Marcelo, F. 2015. The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137, DOI: 10.1021/jacs.5b06787